Natural, clinically proven joint and mobility support pets deserve.
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
Clinically Proven
Works Better & Faster*
PATENTED FORMULA
NATURAL & SUSTAINABLY SOURCED INGREDIENTS
As Seen in
Potent Ingredients, Proven Results.
Antinol®Plus is joint care that works as hard as your pet plays. Backed by 40 years of research and three double-blind clinical trials, this natural, clinically proven formula delivers faster results than glucosamine and chondroitin - because your pet deserves nothing but the best.
Shop NowHarnessing the Power of Nature.
From the pure waters of New Zealand and Antarctica comes a breakthrough in joint care. Antinol Plus combines green-lipped mussel oil and Antarctic krill oil in a potent, natural formula that's as clean and pure as the waters it's sourced from.
Shop Now20 Years of Human Expertise, now for Pets.
From Great HealthWorks - leaders in premium human supplements for over 20 years - comes the same trusted care for your pets' joint and mobility health.
What that means:
Manufactured
in USA from Globally Sourced Ingredients
FDA Registered
Facility
Strictest Quality
Guidelines
Nationwide
Distribution
What Every Pet Parent Deserves:
Every pet deserves the best, which is why our supplements are crafted under strict manufacturing standards and proudly bear the NASC Quality Seal. From ingredient transparency to rigorous quality standards, we ensure your pet gets safe, effective support you can trust.
Look for the Seal
Quality Assurance
Ingredient Transparency
Regulatory Compliance
See for Yourself!
What other pet parents are saying:
Bark & Learn
Explore valuable tips, advice,
and insights into pet health and wellness.
What Are Specialized Pro Resolving Mediators (SPMs)?
If you have researched joint and mobility support for your dog or cat, you have probably run into a lot of talk about omega 3s. What you may not have heard about are specialized pro resolving mediators, or SPMs, and they are one of the most important discoveries in the science of healthy aging. Here is what they are, what they do, and why they matter for keeping your pet happy and active. What are specialized pro resolving mediators?Specialized pro resolving mediators are a family of signaling molecules produced naturally in the body. Think of them as messengers. When your pet's body needs to manage its inflammatory response, SPMs are the molecules that carry the instructions to help bring that response to a healthy close. The main families of SPMs include resolvins, protectins, and maresins. Each plays a role in how the body maintains balance, and each is derived from the fatty acids your pet takes in through their diet. Where SPMs come from This is the part that surprises most pet parents. SPMs are metabolites of omega 3 fatty acids, which means the body builds them out of the omega 3s EPA and DHA. When your pet consumes omega 3s, their body can convert a portion of those fatty acids into these more specialized, more active molecules. The catch is that this conversion process is not always efficient. The body can only make so many SPMs from raw omega 3s, and that capacity declines as pets age. This is why simply flooding the diet with basic omega 3s does not translate into the full benefit that SPMs provide. Inflammation is not the enemy. Lingering inflammation is. Inflammation gets a bad reputation, but it is actually a normal and necessary part of how the body protects and repairs itself. The problem is not inflammation starting. The problem is inflammation that does not switch off when its job is done. For years, the scientific focus was on blocking inflammation. Newer research points to something different and arguably smarter: helping the body resolve inflammation naturally, the way it is designed to. That is the exact job of SPMs. They do not simply suppress a signal. They help the body complete the process and return to balance. Why SPMs matter for your pet's mobilityAs dogs and cats age, everyday movement puts ongoing demands on their joints. Supporting the body's natural inflammation resolution process helps maintain the comfort and flexibility behind the activities your pet loves, from chasing a toy to jumping onto their favorite spot. Because SPMs work with the body's own systems rather than against them, they represent a gentle, targeted approach to lifelong mobility support. How to support your pet's SPM levelsSPMs are naturally found within most marine oils, but not all sources are equal. Some marine oils deliver mostly the raw precursor fatty acids, leaving the conversion work entirely up to your pet's body. Others, produced through specialized processes, preserve a broader spectrum of lipids that better support SPM activity. Antinol Plus is built around this science. Its patented blend of green lipped mussel oil and Antarctic krill oil is produced through a proprietary extraction process designed to preserve the full spectrum of marine lipids that support your pet's natural resolution pathways. Want to understand why this matters compared to a standard fish oil? Read "Green Lipped Mussel Oil vs Fish Oil: What's the Difference?". Frequently asked questions What does SPM stand for?SPM stands for Specialized Pro-Resolving Mediator. Are SPMs the same as omega 3s?No. SPMs are metabolites of omega-3s and are thousands of times more powerful.Green Lipped Mussel Oil vs Fish Oil: What's the Difference?
Fish oil has been the go to omega 3 supplement for pets for decades, but it is not the only marine source of omega 3s, and it may not be the most complete. If you are comparing options for your pet's joint and mobility support, here is what actually separates a standard fish oil from a marine lipid blend built around green lipped mussel oil.Why fish oil became so popularFish oil earned its reputation honestly. It is an accessible, widely available source of omega 3 fatty acids, which support a range of functions from skin and coat health to joint comfort. For a long time, it was the simplest way to get marine omega 3s into a pet's diet. What a standard fish oil deliversMost fish oils provide EPA and DHA and little else. These are valuable fatty acids, but they are precursors, meaning your pet's body still has to do the work of converting them into the more active molecules that support the natural resolution of inflammation. Those active molecules are called specialized pro resolving mediators, or SPMs, and you can read more about them in "What Are Specialized Pro Resolving Mediators?". The limitation is twofold. Fish oil delivers a narrow slice of the marine lipid spectrum, and it leaves the conversion process entirely up to a body whose efficiency can vary with age. There is also the matter of calories. Fish oil is calorie dense, and a daily dose can add up, which works against you when maintaining a healthy weight is one of the most important things you can do for your pet's joints and mobility. Antinol Plus is low in calories by comparison, delivering its full spectrum of marine lipids without the calorie burden of a standard fish oil. What green lipped mussel oil addsGreen lipped mussel oil comes from a species native to the pristine waters of New Zealand, and it delivers a far broader spectrum of fatty acids than EPA and DHA alone. This wider profile is one reason marine lipid blends built around it are gaining attention for mobility support. Antinol Plus takes this further. Its patented blend combines green lipped mussel oil with Antarctic krill oil, pairing two synergistic marine sources to deliver a full spectrum of lipids that support your pet's natural inflammation resolution pathways. The result is a supplement designed to do more than a single source oil, from a formula backed by more than 40 years of research. Why extraction is the hidden differenceHere is the factor most comparisons miss. The way a marine oil is processed determines how much of its delicate lipid profile survives to reach your pet. Aggressive or heat heavy processing can degrade the compounds that make marine oil valuable. Antinol Plus is produced through a unique, proprietary extraction process specifically designed to preserve the full spectrum of marine lipids. Which is right for your pet?A basic fish oil can be a fine starting point for general omega 3 support. But if your goal is targeted, lasting mobility support, a full spectrum marine lipid blend built to preserve and deliver a broader range of active lipids offers something a fish oil cannot match. For most pet parents focused on joint and mobility health, the more complete formula is the better daily investment. Frequently asked questionsIs green lipped mussel oil better than fish oil for dogs?Green lipped mussel oil delivers a broader spectrum of fatty acids than what is found in most fish oils. Can I give my pet both?Many pet parents stack multiple oils, but a full spectrum blend like Antinol Plus is designed to be complete on its own, which can simplify your pet's routine and your budget. Does Antinol Plus contain fish oil?Antinol Plus is built on a patented blend of green lipped mussel oil and Antarctic krill oil rather than standard fish oil.Green-lipped Mussel Oil vs. Glucosamine and Chondroitin
For decades, glucosamine and chondroitin have been the default answer for supporting a dog's joints. They are in nearly every chew on the shelf. But defaults are not always the best option, and a growing body of research is prompting pet parents and veterinarians alike to take a closer look. Here is an honest comparison. The old standard Glucosamine and chondroitin are compounds associated with cartilage, and the logic behind supplementing them is intuitive: give the body more of the building blocks and support the joint. That simple story is a big part of why these ingredients became so widespread. However, when researchers put these ingredients under rigorous testing, the results were not as strong as the marketing had long suggested. What the research shows In recent years, several clinical studies have examined how well glucosamine and chondroitin actually perform, and the findings have raised meaningful questions about how much benefit they deliver on their own. This does not mean pet parents were wrong to try them. It means science has advanced, and there are now more effective, better studied options available. A different mechanism entirely Antinol Plus takes a different approach from glucosamine and chondroitin. Rather than supplying cartilage building blocks and hoping the body puts them to use, Antinol Plus supports the body's own natural process for resolving inflammation, powered by SPMs (specialized pro resolving mediators). You can read how that works in "What Are Specialized Pro Resolving Mediators?". This is a fundamentally more modern approach to mobility support, targeting the biological process behind comfortable movement rather than a single structural ingredient. The clinical evidence behind Antinol Plus This is where the comparison becomes clear. Antinol Plus is backed by four double blind, placebo controlled clinical studies, which is the gold standard of research design. Its patented blend represents more than 40 years of marine lipid science research. Where the older ingredients rely largely on tradition, Antinol Plus is built on evidence you can point to. How fast can you expect results? One of the most common frustrations with traditional joint chews is the long wait, often months, before any change is noticed, if it is noticed at all. Antinol Plus is designed to work faster. Many pet parents see results in as little as 30 days. For a dog whose activity you want to support now, that difference in timeline matters. Making the switch If your dog is currently on a glucosamine and chondroitin product, talk with your veterinarian about whether a clinically studied green-lipped mussel oil approach might be a better fit. Frequently asked questions Does glucosamine really work for dogs? Recent clinical research has raised questions about how much benefit glucosamine provides on its own, prompting many pet parents to explore better studied alternatives. Is Antinol Plus better than glucosamine? Antinol Plus has been clinically proven to work better and faster than glucosamine and chondroitin. How long does Antinol Plus take to work? See visible results in as little as 30 days.@antinolplus